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Organic compounds in which a hydrogen atom or more has been replaced by a halogen atom in an alkane molecule (saturated hydrocarbon chain). Halogen atoms include bromine, chlorine, fluorine, and iodine. Compounds may be in closed ring configurations.
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MK-4101 is a small-molecule Smoothened (SMO) antagonist that inhibits the hedgehog signaling pathway and is provided for research use. It has demonstrated cellular activity in reported assays and is supplied as a solid in multiple pre-weighed quantities.
Small-molecule SMO antagonist useful for hedgehog pathway studies.
Demonstrated cellular activity (IC50 ≈1.1 μM in 293 cells).
Reported cellular activity in mouse cells (IC50 ≈1.5 μM).
Supplied with high reported purity (~99.2%) suitable for research.
Available in multiple pre-weighed quantities, including 50 mg.
Characterized molecular properties (CAS 935273-79-3; formula C24H24F5N5O).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
N-Boc-8-amino-octanoic acid is a Boc-protected amino acid with an eight-carbon aliphatic spacer and a terminal carboxylic acid. It is used as a flexible linker in PROTAC and peptide synthesis; the carboxylic acid can be coupled to amines to form amide bonds, and the Boc protecting group can be removed under mild acidic conditions to reveal the free amine.
Boc-protected amino acid suitable for peptide and PROTAC linker synthesis.